It's been three months since Madeline's children saw her. Now, the police need your help.

Police are appealing for help over a missing Sydney mother who has not been seen in three months.

Madeline Bigatton, aged 48, was last seen wearing a khaki green singlet and three-quarter pants when leaving Sydney a home on the morning of March 25.

When she failed to return home that evening, officers from St George Police Area Command were called and the force began their search.

Later that night, the 48-year-old’s car, a black 2017 Kia Sorento, was located at Cape Solander, Kurnell, some 20 kilometres from where she was last seen.

In appealing for the community’s assistance, New South Wales police said her family hold “serious concerns for her welfare”.

Two men, described to police as Indian Sub-Continental in appearance, located Mrs Bigatton’s car keys the day after she was last seen and St George detectives are keen to talk to them.

The Daily Telegraph report the family have mourned her disappearance since early last month, when they held a memorial service in Kingsgrove.

Anyone with information is urged to contact Crime Stoppers on 1800 333 000.